Turning up the Green Light

Julien Cassereau (1) , Vincent Courdavault (2) , U. Valentin Nägerl (3)

1 MITOVASC-MITOLAB - MitoVasc - Équipe MitoLab (Mitochondrial Pathophysiology)
2 BBV - Biomolécules et biotechnologies végétales
3 IINS - Interdisciplinary Institute for Neuroscience [Bordeaux]

Fluorescent proteins (FPs) have become indispensable tools in biological research for labeling cells and proteins and sensing their biochemical activity. By introducing 'folding mutations', Campbell et al. engineered a new GFP variant with dramatically enhanced cellular brightness and stability, facilitating advanced cellular bioimaging applications in neuroscience and beyond.

Mots clés: brain imaging; fluorescent proteins; protein engineering; super-resolution microscopy

Domaines: Sciences du Vivant [q-bio]

Julien Cassereau, Vincent Courdavault, U. Valentin Nägerl. Turning up the Green Light. Trends in Cell Biology, 2020, ⟨10.1016/j.tcb.2020.12.007⟩. ⟨hal-03115815⟩