CD4+ count‐dependent concentration‐effect relationship of rituximab in rheumatoid arthritis - Archive ouverte HAL Access content directly
Journal Articles British Journal of Clinical Pharmacology Year : 2019

CD4+ count‐dependent concentration‐effect relationship of rituximab in rheumatoid arthritis

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Abstract

Rituximab is approved in rheumatoid arthritis (RA). A substantial decrease in CD4+ count was observed in responders after a single cycle of treatment. This study aimed at describing and quantifying the influence of CD4+ count depletion on the concentration-response relationship of rituximab in RA patients.

Dates and versions

hal-02376303 , version 1 (22-11-2019)

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Amina Bensalem, Denis Mulleman, Gilles Thibault, Nicolas Azzopardi, Philippe Goupille, et al.. CD4+ count‐dependent concentration‐effect relationship of rituximab in rheumatoid arthritis. British Journal of Clinical Pharmacology, 2019, ⟨10.1111/bcp.14102⟩. ⟨hal-02376303⟩

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