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CD4+ count‐dependent concentration‐effect relationship of rituximab in rheumatoid arthritis

Abstract : Rituximab is approved in rheumatoid arthritis (RA). A substantial decrease in CD4+ count was observed in responders after a single cycle of treatment. This study aimed at describing and quantifying the influence of CD4+ count depletion on the concentration-response relationship of rituximab in RA patients.
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https://hal-univ-tours.archives-ouvertes.fr/hal-02376303
Contributor : Nicolas Azzopardi <>
Submitted on : Friday, November 22, 2019 - 3:06:07 PM
Last modification on : Wednesday, December 4, 2019 - 2:36:03 PM

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Amina Bensalem, Denis Mulleman, Gilles Thibault, Nicolas Azzopardi, Philippe Goupille, et al.. CD4+ count‐dependent concentration‐effect relationship of rituximab in rheumatoid arthritis. British Journal of Clinical Pharmacology, Wiley, 2019, ⟨10.1111/bcp.14102⟩. ⟨hal-02376303⟩

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