A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

Xuexin Zhang (1) , Trayambak Pathak , Ryan Yoast , Scott Emrich (2) , Ping Xin , Robert Nwokonko , Martin Johnson , Shilan Wu , Céline Delierneux , Maxime Guéguinou (3) , Nadine Hempel , James Putney , Donald Gill , Mohamed Trebak (1)

1 Center for Cardiovascular Sciences
2 Department of Computer Science and Engineering
3 IC-CGO - Network “Ion channels and Cancer-Canceropole Grand Ouest” [Nantes]

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Cellular Biology

Xuexin Zhang, Trayambak Pathak, Ryan Yoast, Scott Emrich, Ping Xin, et al.. A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction. Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-09593-0⟩. ⟨hal-02372647⟩