M. Chang and J. Lingner, CELL SIGNALING: Tel2 Finally Tells One Story, Science, vol.320, issue.5872, pp.60-61, 2008.
DOI : 10.1126/science.1155132

A. Lustig and T. Petes, Identification of yeast mutants with altered telomere structure., Proceedings of the National Academy of Sciences, vol.83, issue.5, pp.1398-1402, 1986.
DOI : 10.1073/pnas.83.5.1398

T. De-lange, How Telomeres Solve the End-Protection Problem, Science, vol.326, issue.5955, pp.948-952, 2009.
DOI : 10.1126/science.1170633

P. Greenwell, S. Kronmal, S. Porter, J. Gassenhuber, and B. Obermaier, TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene, Cell, vol.82, issue.5, pp.823-829, 1995.
DOI : 10.1016/0092-8674(95)90479-4

K. Runge and V. Zakian, TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.16, issue.6, pp.3094-3105, 1996.
DOI : 10.1128/MCB.16.6.3094

R. Hector, R. Shtofman, A. Ray, B. Chen, and T. Nyun, Tel1p Preferentially Associates with Short Telomeres to Stimulate Their Elongation, Molecular Cell, vol.27, issue.5, pp.851-858, 2007.
DOI : 10.1016/j.molcel.2007.08.007

M. Sabourin, C. Tuzon, and V. Zakian, Telomerase and Tel1p Preferentially Associate with Short Telomeres in S. cerevisiae, Molecular Cell, vol.27, issue.4, pp.550-561, 2007.
DOI : 10.1016/j.molcel.2007.07.016

M. Sabourin and V. Zakian, ATM-like kinases and regulation of telomerase: lessons from yeast and mammals, Trends in Cell Biology, vol.18, issue.7, pp.337-346, 2008.
DOI : 10.1016/j.tcb.2008.04.004

R. Kota and K. Runge, The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA, Nucleic Acids Research, vol.26, issue.6, pp.1528-1535, 1998.
DOI : 10.1093/nar/26.6.1528

R. Kota and K. Runge, Tel2p, a regulator of yeast telomeric length in vivo, binds to single-stranded telomeric DNA in vitro, Chromosoma, vol.108, issue.5, pp.278-290, 1999.
DOI : 10.1007/s004120050379

C. Bénard, B. Mccright, Y. Zhang, S. Felkai, and B. Lakowski, The C. elegans maternal-effect clk-2 is essential for embryonic development, encodes a protein homologous to yeast Tel2p and affects telomere length, Development, vol.128, pp.4045-4055, 2001.

C. Lim, I. Mian, A. Dernburg, and J. Campisi, C. elegans clk-2, a gene that limits life span, encodes a telomere length regulator similar to yeast telomere binding protein Tel2p, Current Biology, vol.11, issue.21, pp.1706-1710, 2001.
DOI : 10.1016/S0960-9822(01)00526-7

URL : https://hal.archives-ouvertes.fr/hal-00293960

N. Jiang, C. Bénard, H. Kébir, E. Shoubidge, and S. Hekimi, Human CLK2 Links Cell Cycle Progression, Apoptosis, and Telomere Length Regulation, Journal of Biological Chemistry, vol.278, issue.24, pp.21678-21684, 2003.
DOI : 10.1074/jbc.M300286200

S. Ahmed, A. Alpi, M. Hengartner, and A. Gartner, C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein, Current Biology, vol.11, issue.24, pp.1934-1944, 2001.
DOI : 10.1016/S0960-9822(01)00604-2

URL : https://hal.archives-ouvertes.fr/in2p3-00115430

M. Shikata, F. Ishikawa, and J. Kanoh, Tel2 Is Required for Activation of the Mrc1-mediated Replication Checkpoint, Journal of Biological Chemistry, vol.282, issue.8, pp.5346-5355, 2007.
DOI : 10.1074/jbc.M607432200

S. Collis, L. Barber, A. Clark, J. Martin, and J. Ward, HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability, Nature Cell Biology, vol.14, issue.4, pp.391-401, 2007.
DOI : 10.1074/jbc.M300286200

H. Takai, R. Wang, K. Takai, H. Yang, and T. De-lange, Tel2 Regulates the Stability of PI3K-Related Protein Kinases, Cell, vol.131, issue.7, pp.1248-1259, 2007.
DOI : 10.1016/j.cell.2007.10.052

C. Anderson and E. Blackburn, Mec1 function in the DNA damage response does not require its interaction with Tel2, Cell Cycle, vol.7, issue.23, pp.3695-3698, 2008.
DOI : 10.4161/cc.7.23.7154

C. Anderson, D. Korkin, D. Smith, S. Makovets, and J. Seidel, Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break, Genes & Development, vol.22, issue.7, pp.854-859, 2008.
DOI : 10.1101/gad.1646208

J. Kanoh and M. Yanagida, Tel2: a common partner of PIK-related kinases and a link between DNA checkpoint and nutritional response?, Genes to Cells, vol.23, issue.12, pp.1301-1304, 2007.
DOI : 10.1111/j.1365-2443.2007.01142.x

T. Hayashi, M. Hatanaka, K. Nagao, Y. Nakaseko, and J. Kanoh, Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits, Genes to Cells, vol.9, issue.12, pp.1357-1370, 2007.
DOI : 10.1111/j.1365-2443.2007.01141.x

P. Stirling, M. Bloom, T. Solanki-patil, S. Smith, and P. Sipahimalani, The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components, PLoS Genetics, vol.19, issue.4, p.1002057, 2011.
DOI : 10.1371/journal.pgen.1002057.s009

A. Shevchenko, A. Roguev, D. Schaft, L. Buchanan, and B. Haberman, Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment, Genome Biology, vol.9, issue.11, p.167, 2008.
DOI : 10.1186/gb-2008-9-11-r167

S. Boulon, N. Marmier-gourrier, B. Pradet-balade, L. Wurth, and C. Verheggen, The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery, The Journal of Cell Biology, vol.6, issue.3, pp.579-595, 2008.
DOI : 10.1016/j.cell.2004.12.024

URL : https://hal.archives-ouvertes.fr/hal-00280860

R. Zhao, Y. Kakihara, A. Gribun, J. Huen, and G. Yang, Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation, The Journal of Cell Biology, vol.78, issue.3, pp.563-578, 2008.
DOI : 10.1016/j.cell.2004.12.024

Z. Horejsi, H. Takai, C. Adelman, S. Collis, and H. Flynn, CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability, Molecular Cell, vol.39, issue.6, pp.839-850, 2010.
DOI : 10.1016/j.molcel.2010.08.037

K. Hurov, C. Cotta-ramusino, and S. Elledge, A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability, Genes & Development, vol.24, issue.17, pp.1939-1950, 2010.
DOI : 10.1101/gad.1934210

N. Izumi, A. Yamashita, A. Iwamatsu, R. Kurata, and H. Nakamura, AAA+ Proteins RUVBL1 and RUVBL2 Coordinate PIKK Activity and Function in Nonsense-Mediated mRNA Decay, Science Signaling, vol.3, issue.116, p.27, 2010.
DOI : 10.1126/scisignal.2000468

H. Takai, Y. Xie, T. De-lange, and N. Pavletich, Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes, Genes & Development, vol.24, issue.18, pp.2019-2030, 2010.
DOI : 10.1101/gad.1956410

M. Rose, P. Novick, J. Thomas, D. Botstein, and G. Fink, A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector, Gene, vol.60, issue.2-3, pp.237-243, 1987.
DOI : 10.1016/0378-1119(87)90232-0

D. Botstein, S. Falco, S. Stewart, M. Brennan, and S. Scherer, Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments, Gene, vol.8, issue.1, pp.17-24, 1979.
DOI : 10.1016/0378-1119(79)90004-0

H. Bourbon, A. Aguilera, A. Ansari, F. Asturias, and A. Berk, A Unified Nomenclature for Protein Subunits of Mediator Complexes Linking Transcriptional Regulators to RNA Polymerase II, Molecular Cell, vol.14, issue.5, pp.553-557, 2004.
DOI : 10.1016/j.molcel.2004.05.011

S. Jha and A. Dutta, RVB1/RVB2: Running Rings around Molecular Biology, Molecular Cell, vol.34, issue.5, pp.521-533, 2009.
DOI : 10.1016/j.molcel.2009.05.016

URL : http://doi.org/10.1016/j.molcel.2009.05.016

J. Huen, Y. Kakihara, F. Ugwu, K. Cheung, and J. Ortega, Rvb1???Rvb2: essential ATP-dependent helicases for critical complexesThis paper is one of a selection of papers published in this special issue entitled 8th International Conference on AAA Proteins and has undergone the Journal's usual peer review process., Biochemistry and Cell Biology, vol.88, issue.1, pp.29-40, 2010.
DOI : 10.1139/O09-122

Z. Jonsson, S. Dhar, G. Narlikar, R. Auty, and N. Wagle, Rvb1p and Rvb2p Are Essential Components of a Chromatin Remodeling Complex That Regulates Transcription of over 5% of Yeast Genes, Journal of Biological Chemistry, vol.276, issue.19, pp.16279-16288, 2001.
DOI : 10.1074/jbc.M011523200

H. Ohdate, C. Lim, T. Kokubo, K. Matsubara, and Y. Kimata, Impairment of the DNA Binding Activity of the TATA-binding Protein Renders the Transcriptional Function of Rvb2p/Tih2p, the Yeast RuvB-like Protein, Essential for Cell Growth, Journal of Biological Chemistry, vol.278, issue.17, pp.14647-14656, 2003.
DOI : 10.1074/jbc.M213220200

P. Gallant, Control of transcription by Pontin and Reptin, Trends in Cell Biology, vol.17, issue.4, pp.187-192, 2007.
DOI : 10.1016/j.tcb.2007.02.005

I. Pinto, D. Ware, and M. Hampsey, The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo, Cell, vol.68, issue.5, pp.977-988, 1992.
DOI : 10.1016/0092-8674(92)90040-J

T. Ito, T. Chiba, R. Ozawa, M. Yoshida, and M. Hattori, A comprehensive two-hybrid analysis to explore the yeast protein interactome, Proceedings of the National Academy of Sciences, vol.98, issue.8, pp.4569-4574, 2001.
DOI : 10.1073/pnas.061034498

S. Porter, P. Greenwell, K. Ritchie, and T. Petes, The DNA-binding Protein Hdf1p (a Putative Ku Homologue) Is Required for Maintaining Normal Telomere Length in Saccharomyces Cerevisiae, Nucleic Acids Research, vol.24, issue.4, pp.582-585, 1996.
DOI : 10.1093/nar/24.4.582

S. Boulton and S. Jackson, Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing, The EMBO Journal, vol.17, issue.6, pp.1819-1828, 1998.
DOI : 10.1093/emboj/17.6.1819

V. Lundblad and J. Szostak, A mutant with a defect in telomere elongation leads to senescence in yeast, Cell, vol.57, issue.4, pp.633-643, 1989.
DOI : 10.1016/0092-8674(89)90132-3

M. Costanzo, A. Baryshnikova, J. Bellay, Y. Kim, and E. Spear, The Genetic Landscape of a Cell, Science, vol.327, issue.5964, pp.425-431, 2010.
DOI : 10.1126/science.1180823

W. Li, J. Zeng, Q. Li, L. Zhao, and T. Liu, Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cancer, Molecular Cancer, vol.9, issue.1, pp.132-143, 2010.
DOI : 10.1186/1476-4598-9-132

P. Flavin, R. A. Mcbryan, J. Cocchiglia, S. Tibbitts, and P. , RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer, FEBS Letters, vol.23, issue.15, 2011.
DOI : 10.1016/j.febslet.2011.07.005

J. Dahlseid, J. Lew-smith, M. Lelivelt, S. Enomoto, and A. Ford, mRNAs Encoding Telomerase Components and Regulators Are Controlled by UPF Genes in Saccharomyces cerevisiae, Eukaryotic Cell, vol.2, issue.1, pp.134-142, 2003.
DOI : 10.1128/EC.2.1.134-142.2003

M. Lim, V. Tang, L. Saux, A. Schueller, J. Bongards et al., Gal11p Dosage-compensates Transcriptional Activator Deletions via Taf14p, Journal of Molecular Biology, vol.374, issue.1, pp.9-23, 2007.
DOI : 10.1016/j.jmb.2007.09.013

A. Ottaviani, E. Gilson, and F. Magdinier, Telomeric position effect: From the yeast paradigm to human pathologies?, Biochimie, vol.90, issue.1, pp.93-107, 2008.
DOI : 10.1016/j.biochi.2007.07.022

Y. Suzuki and M. Nishizawa, The yeast GAL11 protein is involved in regulation of the structure and the position effect of telomeres., Molecular and Cellular Biology, vol.14, issue.6, pp.3791-3799, 1994.
DOI : 10.1128/MCB.14.6.3791

L. Sussel, D. Vannier, and D. Shore, Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure, Genetics, vol.141, pp.873-888, 1995.

X. Zhu, B. Liu, J. Carlsten, J. Beve, and T. Nyström, Mediator Influences Telomeric Silencing and Cellular Life Span, Molecular and Cellular Biology, vol.31, issue.12, pp.2413-2421, 2011.
DOI : 10.1128/MCB.05242-11

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133415

S. Moser, S. Von-elsner, I. Büssing, A. Alpi, and R. Schnabel, Functional Dissection of Caenorhabditis elegans CLK-2/TEL2 Cell Cycle Defects during Embryogenesis and Germline Development, PLoS Genetics, vol.56, issue.4, p.1000451, 2009.
DOI : 10.1371/journal.pgen.1000451.s013

N. Grandin and S. Reed, Differential function and expression of Saccharomyces cerevisiae B-type cyclins in mitosis and meiosis., Molecular and Cellular Biology, vol.13, issue.4, pp.2113-2125, 1993.
DOI : 10.1128/MCB.13.4.2113

N. Grandin, S. Reed, and M. Charbonneau, Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13., Genes & Development, vol.11, issue.4, pp.512-527, 1997.
DOI : 10.1101/gad.11.4.512